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freehearted    
a. 坦白的,率直的,宽大的

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  • Buspirone - Wikipedia
    Buspirone’s principal mechanism of action involves partial agonism at postsynaptic serotonin 5-HT 1A receptors and full agonism at presynaptic 5-HT 1A autoreceptors, which initially reduces serotonergic neuron firing
  • Buspirone - StatPearls - NCBI Bookshelf
    Unlike benzodiazepines and barbiturates, there is no associated risk of physical dependence or withdrawal with buspirone use due to the lack of effects on GABA receptors However, buspirone has little efficacy as an acute anxiolytic as the clinical effect typically takes 2 to 4 weeks to achieve
  • Mechanism of Action of Buspirone - pharmacyfreak. com
    The Mechanism of Action of Buspirone is unique among anxiolytics It acts mainly as a partial agonist at 5-HT1A serotonin receptors, along with mild dopamine D2 antagonism, which together reduce anxiety without CNS depression
  • Buspirone - an overview | ScienceDirect Topics
    Buspirone is an anxiolytic drug that acts as a partial agonist for serotonin (5-HT) 5-HT1A receptors and an antagonist for dopamine D2 autoreceptors It is effective in treating anxiety without causing sedation, physical dependence, or cognitive impairment like benzodiazepines
  • How Buspirone Works in the Brain-Receptor‑Level Insights
    Buspirone treats anxiety by affecting serotonin receptors in the brain An online psychiatrist may explain how this unique mechanism reduces anxiety without heavy sedation or strong dependence risks
  • Buspirone Mechanism of Action | How It Works to Treat Anxiety
    Buspirone primarily acts as a partial agonist at serotonin (5-HT1A) receptors, helping to regulate serotonin levels and reduce anxiety It also affects dopamine receptors to a lesser extent
  • Buspirone: Uses, Interactions, Mechanism of Action | DrugBank
    Acting as a potent agonist in these receptors, buspirone initially causes activation of these autoreceptors and inhibition of 5-HT release It is proposed that buspirone induces desensitization of somatodendritic autoreceptors over time, which may explain the delayed onset of action of the drug
  • Buspirone: An Update on a Unique Anxiolytic Agent
    Buspirone (Buspar) is a azaspirodecanedione anxiolytic agent Its mechanism of action is extremely complex, but current investigations indicate that its main neuropharmacologic effects are mediated by the 5-HT 1A receptors
  • Buspirone (BuSpar) - PsychWiki
    It belongs to the azaspirodecanedione drug class and is a serotonin 5-HT1A receptor partial agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative anxiolytic drugs
  • BuSpar (Buspirone): What You Need to Know - GoodTherapy
    BuSpar is a central nervous system (CNS) selective drug that acts on a single subtype of serotonin (5-HT) receptor It has high affinity for type 1 serotonergic receptors (5HT-1)





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