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  • Excitability as a design principle in the immune system - AAAS
    Here, we propose that excitability, a concept from dynamical systems, provides these goals in diverse contexts An excitable system produces a large response pulse when stimulus crosses a threshold and then shuts itself down, followed by a refractory period
  • Excitability as a Design Principle in the Immune System
    We suggest that excitability is a recurring design principle in immunology and show that circuits with excitable potential recur throughout the immune system To explore how many excitable circuits exist, we scanned a large class of two-cytokine and two-cell circuits
  • Excitability: Types I, II, and III - University of Utah
    In class 2 excitability, the steady-state I-V curve has no local maximum; instead, depolarization above the local maximum of the instantaneous I-V curve causes increasing outward current
  • Dynamical Systems in Neuroscience - Archive. org
    Different classes of excitability occur because neurons have different bifurcations of resting and spiking states – a phenomenon first explained by Rinzel and Ermen- trout (1989)
  • Membrane physiology and the basis of excitability
    In excitable cells the membrane potential is not constant When the cell is stimulated, the membrane potential is changing These changes in membrane potential are due to changes in permeability of plasma membrane to different ions For example, when a neuron is stimulated, this will result in increased permeability to Na+
  • Excitable behaviors - arXiv. org
    The discussion of excitability in this chapter is an attempt to revisit one of the most basic properties of biological systems in the classical language of nonlinear circuit theory
  • Intrinsic excitability mechanisms of neuronal ensemble formation
    We conclude that the increase in excitability induced by optogenetic or electrical stimulation is asso-ciated with increases in membrane resistance, but not with membrane resting potential





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