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  • Normal Liver Histology 101 - AASLD
    The hepatic acinus is based upon blood perfusion throughout the liver parenchyma The acinus is organized as a “diamond,” with PTs at the corners of the short axis and CVs at the corners of the long axis (Figure 3) The acinus is arbitrarily divided into three zones based upon perfusion
  • Liver, Gall Bladder, and Pancreas - University of Oklahoma Health . . .
    Some acini reveal the centrally located centroacinar cells These cells are the beginning of intercalated ducts lined with a simple low columnar or cuboidal epithelium
  • Liver MPS Platforms – Pitt Trace
    When placed under flow the system can mimic the gradual oxygen tensions (Zone 1 through Zone 3) of the sinus, replicating the metabolic zonation of the acinus The vLAMPS can be constructed with both primary liver cells and patient-derived liver induced pluripotent stem cells (iPSCs)
  • Structural organization of the liver – Veterinary Histology
    The acinus (plural: acini) highlights the hepatic blood flow and metabolic activity, and is particularly useful when considered liver disease or pathology The acinus is shaped as a triangle





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